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头孢比普、利奈唑胺、替加环素及其他23种抗菌药物对中国金黄色葡萄球菌分离株的体外活性

In vitro activity of ceftobiprole, linezolid, tigecycline, and 23 other antimicrobial agents against Staphylococcus aureus isolates in China.

作者信息

Wang Hui, Liu Yudong, Sun Hongli, Xu Yingchun, Xie Xiuli, Chen Minjun

机构信息

Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China.

出版信息

Diagn Microbiol Infect Dis. 2008 Oct;62(2):226-9. doi: 10.1016/j.diagmicrobio.2008.06.003. Epub 2008 Jul 23.

DOI:10.1016/j.diagmicrobio.2008.06.003
PMID:18653301
Abstract

We investigated the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in China and determined the susceptibility of S. aureus to 26 antimicrobial agents, including ceftobiprole, linezolid, and tigecycline. A total of 798 isolates were collected and tested by agar dilution. The mean prevalence of MRSA was 50.4%, the highest in Shanghai (80.3%), followed by those in Beijing (55.5%) and Shenyang (50.0%). Only 4.2% to 12.6% of MRSA were susceptible to erythromycin, fluoroquinolones, gentamicin, and tetracycline. All isolates were susceptible to teicoplanin, vancomycin, linezolid, tigecycline, and ceftobiprole.

摘要

我们调查了中国耐甲氧西林金黄色葡萄球菌(MRSA)的流行情况,并测定了金黄色葡萄球菌对26种抗菌药物的敏感性,这些抗菌药物包括头孢比普、利奈唑胺和替加环素。共收集了798株菌株,并通过琼脂稀释法进行检测。MRSA的平均流行率为50.4%,在上海最高(80.3%),其次是北京(55.5%)和沈阳(50.0%)。仅4.2%至12.6%的MRSA对红霉素、氟喹诺酮类、庆大霉素和四环素敏感。所有菌株对替考拉宁、万古霉素、利奈唑胺、替加环素和头孢比普敏感。

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