Lai V, Wong Y C, Poon W L, Fu Y P, Lam T C, Yuen S C
Department of Radiology, Tuen Mun Hospital, Tuen Mun, Hong Kong, China.
AJNR Am J Neuroradiol. 2008 Nov;29(10):1995-7. doi: 10.3174/ajnr.A1219. Epub 2008 Jul 24.
Radiation-induced peripheral nerve tumor, in particular a benign entity such as a neurofibroma, is rare, with only a few cases being reported so far. We demonstrate a case of radiation-induced neurofibromata along the left cervical nerve roots in a man with a background of localized targeted hypofractionated radiation therapy as adjuvant treatment for left cervical nodal metastasis complicating nasopharyngeal carcinoma. The toxicity of high-dose radiation in a hypofractionated regime is also stressed.
辐射诱发的周围神经肿瘤，尤其是像神经纤维瘤这样的良性肿瘤，非常罕见，迄今为止仅有少数病例报道。我们展示了一例在一名男性患者中沿左侧颈神经根出现的辐射诱发神经纤维瘤病例，该患者曾接受局部适形分割放疗作为辅助治疗，用于鼻咽癌伴发的左侧颈部淋巴结转移。文中还强调了大剂量适形分割放疗的毒性。
