Chandrasoma P, Shibata D, Radin R, Brown L P, Koss M
Cancer. 1986 May 15;57(10):2022-5. doi: 10.1002/1097-0142(19860515)57:10<2022::aid-cncr2820571023>3.0.co;2-d.
The authors report a case of malignant peripheral nerve sheath tumor arising in an adrenal ganglioneuroma in an adult. This is the first such case occurring in the absence of a history of childhood neuroblastoma treated with radiation, and provides evidence that such a transformation can occur spontaneously. The neoplasm demonstrated a highly malignant biologic behavior with rapid growth, local recurrence, and metastasis.
作者报告了一例成人肾上腺神经节神经瘤中发生的恶性外周神经鞘瘤病例。这是首例在无儿童期神经母细胞瘤放疗史的情况下发生的此类病例,为这种转变可自发发生提供了证据。该肿瘤表现出高度恶性的生物学行为,生长迅速、局部复发并发生转移。