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枸橼酸氯米芬对狒狒围排卵期子宫内膜发育的影响。

Effect of clomiphene citrate upon periovulatory endometrial development in the baboon.

作者信息

Eley R M, Gould K G, Eley D S, Suleman M A, Tarara R P

机构信息

Institute of Primate Research, National Museums of Kenya, Nairobi.

出版信息

J Med Primatol. 1991;20(2):49-57.

PMID:1865481
Abstract

Endometrial histology in baboons (Papio cynocephalus anubis) was evaluated after five days of clomiphene citrate (CC) treatment initiated on either cycle day six (n = 8) or ten (n = 4). Biopsies performed before and after a human chorionic gonadotropin (hCG) induced ovulation were compared to non-CC treated controls. Although CC had a definite antiestrogenic effect on perineal skin, no significant effect of endometrial proliferation was demonstrable.

摘要

在第6天(n = 8)或第10天(n = 4)开始给予枸橼酸氯米芬(CC)治疗5天后,对狒狒(东非狒狒)的子宫内膜组织学进行了评估。将人绒毛膜促性腺激素(hCG)诱导排卵前后进行的活检与未接受CC治疗的对照组进行比较。尽管CC对会阴皮肤有明确的抗雌激素作用,但未显示出对子宫内膜增殖有显著影响。

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Arch Gynecol Obstet. 1995;256(1):17-22. doi: 10.1007/BF00634343.