Hirose Y, Konda S, Sasaki K, Konishi F, Takazakura E
Department of Internal Medicine, Kanazawa Medical University, Ishikawa, Japan.
Jpn J Med. 1991 Jan-Feb;30(1):43-6. doi: 10.2169/internalmedicine1962.30.43.
A 63-year-old male, who had undergone angiography using thorium dioxide (Thorotrast) at the age of 15 for investigation of a giant hemangioma on his left thigh, developed anemia in September 1986 (47 yrs after the angiography). A diagnosis of erythroleukemia was made from a bone marrow study which showed 56.4% megaloblastoid erythroblasts and 12.8% myeloblasts. Autopsy revealed Thorotrast deposition in the liver, spleen, bone marrow, and lymph nodes, and monotonous proliferation of myeloblasts in the bone marrow. He also had differentiated tubular adenocarcinoma of the posterior wall of the stomach.
一名63岁男性，15岁时因左大腿巨大血管瘤接受二氧化钍（钍造影剂）血管造影检查，1986年9月（血管造影后47年）出现贫血。骨髓检查诊断为红白血病，其中巨幼样成红细胞占56.4%，原始粒细胞占12.8%。尸检发现肝脏、脾脏、骨髓和淋巴结中有钍造影剂沉积，骨髓中原始粒细胞呈单一性增殖。他还患有胃后壁分化型管状腺癌。
