Kobza Richard, Roos Markus, Toggweiler Stefan, Zuber Michel, Erne Paul
Division of Cardiology, Kantonsspital Luzern, Spitalstrasse, CH-6000 Luzern 16, Switzerland.
Resuscitation. 2008 Nov;79(2):265-72. doi: 10.1016/j.resuscitation.2008.05.013. Epub 2008 Jul 24.
The ECG discrimination of ventricular tachycardia (VT) vs. supraventricular tachycardia (SVT) is both important and often difficult. In this study, we tested the hypothesis that recorded digital cardiac acoustical data reflect hemodynamic changes that can be used for VT detection.
We studied 57 subjects (42 males, mean age 57, range 24-83 years) who had undergone electrophysiological testing for known and suspected cardiac arrhythmias. Acoustic cardiography (Audicor, Inovise Medical, Inc.) was performed during each subject's electrophysiological study. We evaluated the ability of S1 intensity and S1 variability to discriminate between VT and supraventricular rhythm.
The 57 subjects had 17 episodes of VT and 76 episodes of supraventricular rhythm--including 22 episodes of SVT. VT had a lower S1 intensity and higher S1 variability than supraventricular rhythm (2.63+/-1.78 mV vs. 4.70+/-5.03 mV and 0.45+/-0.24 vs. 0.21+/-0.11, respectively). Conversely, left bundle branch block, right bundle branch block or SVT did not affect either S1 intensity or its variability. Ventricular pacing increased S1 variability but did not affect S1 intensity. The sensitivity of S1 variability for detecting VT was 50% at 100% specificity.
VT is associated with both decreased S1 intensity and increased beat-to-beat S1 variability. The electronic recording and digital processing of digital heart sound data is useful for identifying VT and may facilitate the differential diagnosis of clinically important tachyarrhythmias, particularly in emergency situations where advanced techniques such as electrophysiology studies are not available.
心电图鉴别室性心动过速(VT)与室上性心动过速(SVT)既重要又常常困难。在本研究中,我们检验了以下假设:记录的数字心脏声学数据反映了可用于VT检测的血流动力学变化。
我们研究了57名受试者(42名男性,平均年龄57岁,范围24 - 83岁),他们因已知和疑似心律失常接受了电生理检查。在每位受试者的电生理研究期间进行了心音图检查(Audicor,Inovise Medical公司)。我们评估了S1强度和S1变异性鉴别VT与室上性心律的能力。
57名受试者有17次VT发作和76次室上性心律发作,包括22次SVT发作。VT的S1强度低于室上性心律,S1变异性高于室上性心律(分别为2.63±1.78 mV对4.70±5.03 mV以及0.45±0.24对0.21±0.11)。相反,左束支传导阻滞、右束支传导阻滞或SVT均不影响S1强度或其变异性。心室起搏增加了S1变异性,但不影响S1强度。S1变异性检测VT的敏感性在特异性为100%时为50%。
VT与S1强度降低和逐搏S1变异性增加有关。数字心音数据的电子记录和数字处理有助于识别VT,并可能促进对临床上重要的快速性心律失常的鉴别诊断,特别是在无法进行电生理研究等先进技术的紧急情况下。