Leng Gareth, Meddle Simone L, Douglas Alison J
Centre for Integrative Physiology, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, UK.
Curr Opin Pharmacol. 2008 Dec;8(6):731-4. doi: 10.1016/j.coph.2008.07.001. Epub 2008 Aug 6.
Oxytocin released within the brain from both magnocellular and parvocellular systems of the hypothalamus has diverse effects on behavior. When oxytocin is released within the brain, its effects are to diminish fearfulness; this not only encourages social investigation of newcomers, but also may enhance a tendency to express aggression toward an intruder. Oxytocin supports social recognition, redirects behavior away from feeding directed behavior toward sexual behavior, and facilitates the formation of social bonds. This system, which depends not only upon release of oxytocin but also on oxytocin receptor distribution within the brain, becomes particularly important at parturition, when a bond is first formed between mother and offspring.
下丘脑的大细胞和小细胞系统释放到大脑中的催产素对行为有多种影响。当催产素在大脑中释放时,其作用是减轻恐惧;这不仅鼓励对新来者进行社交探究,还可能增强对入侵者表现出攻击性的倾向。催产素支持社会识别,将行为从觅食导向行为转向性行为,并促进社会纽带的形成。这个系统不仅依赖于催产素的释放,还依赖于大脑中催产素受体的分布,在分娩时,当母亲和后代之间首次形成纽带时,这个系统变得尤为重要。