分枝杆菌感染的免疫学：特别提及副结核分枝杆菌鸟亚种。
Immunology of mycobacterial infections: with special reference to Mycobacterium avium subspecies paratuberculosis.
作者信息
Sohal Jagdeep Singh, Singh S V, Tyagi P, Subhodh Swati, Singh P K, Singh A V, Narayanasamy K, Sheoran Neelam, Singh Sandhu Komal
机构信息
Central Institute for Research on Goats, Makhdoom, P.O. Farah, District Mathura 281122, Uttar Pradesh, India.
出版信息
Immunobiology. 2008;213(7):585-98. doi: 10.1016/j.imbio.2007.11.002. Epub 2008 Mar 4.
The interplay between mycobacteria and host determines the outcome of infection. After uptake of mycobacteria by macrophages, several possible scenarios may emerge; mycobacteria may be destroyed immediately or there is establishment of persistent infection. This review is focused around mycobacteria-host interactions with reference to Mycobacterium avium subspecies paratuberculosis (MAP) infection and highlights protective mechanisms involved in order to design vaccines and other control strategies.
分枝杆菌与宿主之间的相互作用决定了感染的结果。巨噬细胞摄取分枝杆菌后，可能会出现几种情况：分枝杆菌可能会立即被消灭，或者会建立持续性感染。本综述围绕鸟分枝杆菌副结核亚种（MAP）感染，聚焦于分枝杆菌与宿主的相互作用，并着重介绍相关的保护机制，以便设计疫苗和其他控制策略。
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