Levenson M J, Parisier S C, Dolitsky J, Bindra G
Department of Otolaryngology-Head and Neck Surgery, Manhattan Eye, Ear and Throat Hospital, New York, NY 10021.
Laryngoscope. 1991 Aug;101(8):821-4. doi: 10.1288/00005537-199108000-00004.
Ciprofloxacin, a fluorinated quinolone with high efficacy against Pseudomonas aeruginosa, was used in the treatment of 10 consecutive patients with malignant external otitis. All patients had skull base osteomyelitis documented by nuclear and computed tomography (CT) scans. Dosages of 1.5 g of ciprofloxacin daily were used for a mean average of 10 weeks. All patients were considered cured with a minimum follow-up of 18 months after completion of therapy. A new classification of malignant external otitis (MEO) is presented.
环丙沙星是一种对铜绿假单胞菌有高效的氟喹诺酮类药物,用于连续治疗10例恶性外耳道炎患者。所有患者均经核素扫描和计算机断层扫描(CT)证实有颅底骨髓炎。环丙沙星的用量为每日1.5克,平均用药10周。所有患者均被视为治愈,治疗结束后至少随访18个月。本文提出了恶性外耳道炎(MEO)的一种新分类。