Int J Cardiol. 2009 Jul 10;135(3):e85-6. doi: 10.1016/j.ijcard.2008.04.047. Epub 2008 Jul 25.
Tako-Tsubo cardiomyopathy (TTC) which is usually precipitated by profound emotional and physical stress has been widely reported in the past. In this case we report a young female patient who developed sudden dyspnea and palpitation after an profound stress (fierce argument).The patient had characteristic feature of progressive pulmonary edema. Her symptom worsened gradually leading to cardiopulmonary arrest in a few hours from the onset. After resuscitation an immediately performed echocardiography showed a severe mitral regurgitation due to rupture of antromedial papillary muscle. Left ventricular function showed akinetic mid-to-distal portion of the left ventricular chamber and hyperkinetic in basal segment. Inotrop infusion and aortic balloon pump placement was done because of unstable homodynamics. Semi-elective surgical valve replacement was performed. One year after the acute event the patient remained asymptomatic. Clinicians should recognize that Tako-Tsubo cardiomyopathy is one etiology of acute pulmonary edema with normal coronary artery finding.
心尖球囊样综合征（Tako-Tsubo 心肌病）通常由剧烈的情绪和身体应激引起，过去已有广泛报道。在本例中，我们报告了一位年轻女性患者，她在经历强烈的应激（激烈争吵）后出现突发呼吸困难和心悸。患者具有进行性肺水肿的特征性表现。她的症状逐渐恶化，从发病开始几个小时后导致心肺骤停。复苏后立即进行的超声心动图显示由于前内侧乳头肌破裂导致严重的二尖瓣反流。左心室功能显示左心室中部至远端呈无运动，基底段呈高运动。由于血流动力学不稳定，给予正性肌力药物输注和主动脉球囊泵放置。进行了半择期手术瓣膜置换。急性事件发生一年后，患者仍无症状。临床医生应认识到，心尖球囊样综合征是伴有正常冠状动脉的急性肺水肿的一种病因。
