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体外生命支持作为导致 Takotsubo 心肌病的难治性重度心源性休克的终极策略:一种新的有效治疗选择。

Extracorporeal life support as ultimate strategy for refractory severe cardiogenic shock induced by Tako-tsubo cardiomyopathy: a new effective therapeutic option.

机构信息

Cardiac Surgery, Medical and Surgical Critical Care Department, University of Florence, Viale Morgagni 85, Florence, Italy.

出版信息

Artif Organs. 2009 Oct;33(10):866-70. doi: 10.1111/j.1525-1594.2009.00825.x. Epub 2009 Jul 22.

Abstract

We report a possible new therapeutic strategy, using extracorporeal cardiopulmonary support (ECLS), for severe refractory cardiogenic shock (SRCS) in a patient with Tako-tsubo cardiomyopathy (TC). TC is a syndrome characterized by left ventricular wall motion abnormalities, without coronary artery disease, mimicking the diagnosis of acute coronary syndrome. This ventricular dysfunction can be reversible; however, it can progress into refractory cardiogenic shock with limited therapeutic options available. For the first time in a Tako-tsubo patient with refractory cardiogenic shock, we used ECLS treatment in order to rest the heart, sustain circulation and end-organ perfusion, and promote potential ventricular recovery. ECLS might be the selected treatment for SRCS in patients with TC, and seems to be an effective and useful ultimate therapeutic strategy for preventing death.

摘要

我们报告了一种可能的新治疗策略,即使用体外心肺支持(ECLS)治疗 Takotsubo 心肌病(TC)患者的严重难治性心源性休克(SRCS)。TC 是一种以左心室壁运动异常为特征的综合征,无冠状动脉疾病,类似于急性冠状动脉综合征的诊断。这种心室功能障碍是可逆的;然而,它可能进展为难治性心源性休克,治疗选择有限。这是首例使用 ECLS 治疗难治性心源性休克的 Takotsubo 患者,我们使用 ECLS 治疗以减轻心脏负担、维持循环和终末器官灌注,并促进潜在的心室恢复。ECLS 可能是 TC 患者 SRCS 的首选治疗方法,并且似乎是一种预防死亡的有效且有用的最终治疗策略。

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