[卵巢早衰：采取哪些方法？]

[Premature ovarian failure: which approaches?].

作者信息

Belaisch-Allart J, Mayenga J-M, Grefenstete I, Mokdad A, Moumin H

机构信息

Service de gynécologie-obstétrique et médecine de la reproduction, centre hospitalier des Quatre-Villes, Site-de-Sèvres, 141, Grande-Rue, 92318 Sèvres cedex, France.

出版信息

Gynecol Obstet Fertil. 2008 Sep;36(9):882-5. doi: 10.1016/j.gyobfe.2008.06.014. Epub 2008 Jul 26.

DOI:10.1016/j.gyobfe.2008.06.014

PMID:18657462

Abstract

Premature ovarian failure (POF) occurs in one case of 10,000 in women below the age of 20, one case of 1000 below 30 and 1% in women before the age of 40. In 80% of POF cases, the etiology is unknown, except for Turner syndrome. Spontaneous fertility is very weak, only 3 to 10% of the patients will have natural conception. If the diagnosis is confirmed, ovarian stimulation usually fails. When fertility is desired, the alternative treatments are oocyte and/or embryo donation or adoption and "learn to be happy just in couple". Psychological management is always necessary.

摘要

卵巢早衰（POF）在20岁以下女性中的发病率为万分之一，30岁以下女性中为千分之一，40岁之前女性中为1%。在80%的卵巢早衰病例中，除特纳综合征外，病因不明。自然受孕几率非常低，只有3%至10%的患者会自然受孕。如果确诊，卵巢刺激通常无效。当有生育需求时，替代治疗方法是卵母细胞和/或胚胎捐赠或领养，以及“学会夫妻间自得其乐”。心理疏导总是必要的。