Knisely Janet S, Wunsch Martha J, Cropsey Karen L, Campbell Eleanor D
Department of Psychiatry, Virginia Commonwealth University, Richmond, VA 23298, USA.
J Subst Abuse Treat. 2008 Dec;35(4):380-6. doi: 10.1016/j.jsat.2008.02.001. Epub 2008 Jul 26.
The Prescription Opioid Misuse Index (POMI) was developed and used in a larger study designed to assess correlates of OxyContin abuse in pain patients prescribed OxyContin, patients treated for OxyContin addiction, and individuals incarcerated for OxyContin-related charges. The POMI was administered to 40 subjects with addiction problems and 34 pain patients who had received OxyContin for pain. Receiver operating characteristic curve analysis indicated that endorsing two or more of six items reliably classified a person as at risk for misuse of their medication. When comparing drug abuse/dependence in subjects classified as misusers or users, significantly more misusers received a diagnosis for alcohol (p < .01), illicit drugs (p < .05), and other prescription medications (p < .05) and reported greater lifetime use of alcohol (p < .002) and illicit drugs (p < .01). No between-group differences were found regarding psychiatric problems. The POMI appears to be a sensitive and specific instrument for identifying patients who misuse opioid medications.
处方阿片类药物滥用指数（POMI）是在一项更大规模的研究中开发并使用的，该研究旨在评估开具奥施康定的疼痛患者、接受奥施康定成瘾治疗的患者以及因与奥施康定相关指控而被监禁的个体中奥施康定滥用的相关因素。POMI应用于40名有成瘾问题的受试者和34名因疼痛接受过奥施康定治疗的疼痛患者。受试者工作特征曲线分析表明，认可六项中的两项或更多项可可靠地将一个人归类为有药物滥用风险。在比较被归类为滥用者或使用者的受试者的药物滥用/依赖情况时，滥用者被诊断为酒精（p < 0.01）、非法药物（p < 0.05）和其他处方药（p < 0.05）的比例显著更高，并且报告的酒精（p < 0.002）和非法药物终身使用量更大（p < 0.01）。在精神问题方面未发现组间差异。POMI似乎是一种用于识别滥用阿片类药物患者的敏感且特异的工具。
