Fracheboud Y, King P J
Friedrich Miescher-Institut, Basel, Switzerland.
Mol Gen Genet. 1991 Jul;227(3):397-400. doi: 10.1007/BF00273929.
Auxin (indole-3-acetic acid) is considered to be an important signalling molecule in the regulation of plant growth and development but neither auxin synthesis nor its mode of action is clearly understood. To identify genes involved in these processes, mutations were sought that altered the auxin requirement of plant tissues for growth. For the first time mutant plants were obtained that carry a recessive mutation at a single nuclear locus (aux1) which results in an absolute requirement for exogenous auxin for normal growth. In the absence of auxin treatment, mutant plants undergo premature senescence and die.
生长素（吲哚 - 3 - 乙酸）被认为是植物生长和发育调控中一种重要的信号分子，但生长素的合成及其作用方式都尚未完全清楚。为了鉴定参与这些过程的基因，研究人员寻找了能够改变植物组织生长对生长素需求的突变体。首次获得了在单个核基因座（aux1）携带隐性突变的突变体植株，该突变导致植株正常生长绝对需要外源生长素。在没有生长素处理的情况下，突变体植株会过早衰老并死亡。
