Underberg James A, Hays Richard
Division of General Internal Medicine, New York University Medical School, New York, NY USA.
J Fam Pract. 2007 Dec;56(12 Suppl New):S24-31.
Hypertriglyceridemia is a commonly encountered problem in primary care practice. In 2002, the Third National Health and Nutrition Examination Survey reported that among adults 20 years of age and older, 30% had a triglyceride (TG) level greater than 150 mg/dL, and among people 50 years of age and older, the prevalence was 42.8%. Recent data suggest that elevated TG levels are an independent risk factor for cardiovascular disease (CVD). It is important, therefore, that clinicians identify patients with hypertriglyceridemia and initiate treatment as appropriate. In this article, we use a case study to illustrate the appropriate identification and treatment of a patient at risk. We also review the etiology of hypertriglyceridemia, its association with CVD, the recommended approach to treatment, and the efficacy and tolerability of therapeutic options.
高甘油三酯血症是基层医疗实践中常见的问题。2002年，第三次全国健康与营养检查调查显示，20岁及以上的成年人中，30%的人甘油三酯（TG）水平高于150mg/dL，50岁及以上人群的患病率为42.8%。近期数据表明，甘油三酯水平升高是心血管疾病（CVD）的独立危险因素。因此，临床医生识别出高甘油三酯血症患者并进行适当治疗非常重要。在本文中，我们通过一个案例研究来说明对有风险患者的适当识别和治疗。我们还将回顾高甘油三酯血症的病因、其与心血管疾病的关联、推荐的治疗方法以及治疗选择的疗效和耐受性。
