Gagliardi Luigi, Bellù Roberto, Cardilli Viviana, De Curtis Mario
Division of Neonatology and Pediatrics, Ospedale Versilia, Lido di Camaiore, Italy.
J Pediatr Gastroenterol Nutr. 2008 Aug;47(2):206-10. doi: 10.1097/MPG.0b013e318174e855.
Incidence and non-nutritional risk factors were estimated for necrotising enterocolitis in 2035 very low birth weight infants, admitted to 14 tertiary-level neonatal intensive care units in Lombardy, northern Italy. There were 62 necrotising enterocolitis cases, with an overall incidence of 3.1%. After adjustment for gestational age and centre, the risk factors were mechanical ventilation, patent ductus arteriosus, and late-onset sepsis, whereas surfactant treatment was associated with decreased risk. Significant variations in necrotising enterocolitis incidence among hospitals were found.
对意大利北部伦巴第地区14家三级新生儿重症监护病房收治的2035例极低出生体重儿坏死性小肠结肠炎的发病率及非营养性风险因素进行了评估。坏死性小肠结肠炎病例有62例，总发病率为3.1%。在对胎龄和中心进行调整后，风险因素为机械通气、动脉导管未闭和晚发性败血症，而表面活性剂治疗与风险降低相关。发现各医院坏死性小肠结肠炎发病率存在显著差异。
