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下颌骨骨内血管瘤。一例病例报告及文献复习。

Intraosseous mandibular hemangioma. A case report and review of the literature.

作者信息

Gómez Oliveira Guillermo, García-Rozado Alvaro, Luaces Rey Ramón

机构信息

Oral and Maxillofacial Surgery Department, CHU Juan Canalejo, La Coruña, Spain.

出版信息

Med Oral Patol Oral Cir Bucal. 2008 Aug 1;13(8):E496-8.

PMID:18667983
Abstract

Intraosseous vascular lesions are rare conditions, comprising only 0.5% to 1% of all intraosseous tumors. They mainly occur in the second decade of life especially in women. The most common locations are the vertebral column and skull; nevertheless, the mandible is a quite rare location. According to the World Health Organization, hemangiomas are benign vasoformative neoplasms of endothelial origin. However, the origin of central hemangioma is debatable. Some authors believe that it is a true neoplasm, whereas others state it is a hamartomatous lesion. Clinically, the patient may be completely symptom-free or may present discomfort, pulsatile bleeding, bluish discoloration, mobile teeth, derangement of the arch form or accelerated dental exfoliation. Most frequently radiographic finding is a multilocular radiolucent image with honeycombs or soap bubble appearance. Differential diagnosis includes neoplasms such as ameloblastoma, cystic lesions such as residual cyst, keratocyst and fibro-osseous lesions such as fibrous dysplasia. There are some therapeutic alternatives, although wide surgical excision remains as the gold standard. We now present a case report of a 51-year-old woman diagnosed in a mandibular hemangioma. Clinical, radiological and histological features of this unusual tumor are described.

摘要

骨内血管性病变较为罕见,仅占所有骨内肿瘤的0.5%至1%。它们主要发生在生命的第二个十年,尤其多见于女性。最常见的部位是脊柱和颅骨;然而,下颌骨是一个相当罕见的发病部位。根据世界卫生组织的定义,血管瘤是内皮起源的良性血管形成性肿瘤。然而,中央型血管瘤的起源存在争议。一些作者认为它是一种真正的肿瘤,而另一些人则称其为错构瘤性病变。临床上,患者可能完全没有症状,也可能出现不适、搏动性出血、皮肤发蓝、牙齿松动、牙弓形态紊乱或牙齿过早脱落。最常见的影像学表现是呈蜂窝状或肥皂泡样的多房性透射影像。鉴别诊断包括成釉细胞瘤等肿瘤、残余囊肿等囊性病变、角化囊肿以及纤维发育异常等纤维-骨病变。虽然广泛的手术切除仍然是金标准,但仍有一些治疗选择。我们现在报告一例51岁女性下颌骨血管瘤的病例。描述了这种罕见肿瘤的临床、放射学和组织学特征。

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