Fronzes Remi, Remaut Han, Waksman Gabriel
School of Crystallography, Institute of Structural and Molecular Biology, Birkbeck College/University College London, London, UK.
EMBO J. 2008 Sep 3;27(17):2271-80. doi: 10.1038/emboj.2008.155.
Bacteria commonly expose non-flagellar proteinaceous appendages on their outer surfaces. These extracellular structures, called pill or fimbriae, are employed in attachment and invasion, biofilm formation, cell motility or protein and DNA transport across membranes. Over the past 15 years, the power of molecular and structural techniques has revolutionalized our understanding of the biogenesis, structure, function and mode of action of these bacterial organelles. Here, we review the five known classes of Gram-negative non-flagellar appendages from a biosynthetic and structural point of view.
细菌通常在其外表面暴露非鞭毛蛋白附属物。这些被称为菌毛或纤毛的细胞外结构用于附着和侵袭、生物膜形成、细胞运动或蛋白质及DNA的跨膜运输。在过去15年中，分子和结构技术的力量彻底改变了我们对这些细菌细胞器的生物发生、结构、功能及作用方式的理解。在此，我们从生物合成和结构的角度综述革兰氏阴性非鞭毛附属物的五个已知类别。
