Gasparello-Almeida Rozana, Feitosa-Oliveira Sheila Knupp
Unit of Pediatric Rheumatology, Universidade Federal do Rio de Janeiro/Instituto de Puericultura e Pediatria Martagão Gesteira, Rio de Janiero, Brazil.
Isr Med Assoc J. 2008 Jun;10(6):473-4.
Neonatal lupus erythematosus is an uncommon transplacentally acquired autoimmune disorder. The most common clinical manifestations are skin rash, congenital atrioventricular block, thrombocytopenia, leukopenia, anemia, and hepatosplenomegaly. Usually, the skin rash resembles subacute cutaneous lupus, but different forms of rash have been reported in neonatal lupus erythematosus and some are rare forms. NLE should be suspected in babies with atypical skin lesions, even if present at birth.
