Almeida Herrero Fernando, López Lozano Raúl, Silvestre Muñoz Antonio
Servicio Cirugía Ortopédica y Traumatología, Hospital Clinico Universitario, Valencia, España.
Acta Ortop Mex. 2008 Mar-Apr;22(2):80-4.
Serum C-Reactive Protein was measured serially in 45 patients treated with uncomplicated primary total hip and knee arthroplasty (24 THR y 21 TKR). Blood specimens were obtained before surgery, on surgery day and on the 2nd, 3rd, 5th, 13th, 42nd and 150th postoperative days. In both groups serum CRP levels increased rapidly after surgery, with maximum levels on second postoperative day, higher in the TKR group and decreased gradually to preoperative levels on day 150, but still high on 42nd day. Levels returned to normal after surgery at the same time in both groups and no significant differences were found. Rising CRP levels after the third postoperative day may suggest a surgery complication such as infection.
对45例行单纯初次全髋关节置换术（THR，24例）和全膝关节置换术（TKR，21例）的患者连续测定血清C反应蛋白。在手术前、手术当天以及术后第2天、第3天、第5天、第13天、第42天和第150天采集血样。两组患者术后血清CRP水平均迅速升高，术后第2天达到最高水平，TKR组更高，术后第150天逐渐降至术前水平，但在第42天时仍较高。两组患者术后CRP水平同时恢复正常，未发现显著差异。术后第3天CRP水平升高可能提示手术并发症，如感染。
