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人类中间纵束的描绘:一项定量、活体的扩散张量磁共振成像研究。

Delineation of the middle longitudinal fascicle in humans: a quantitative, in vivo, DT-MRI study.

作者信息

Makris Nikos, Papadimitriou George M, Kaiser Jonathan R, Sorg Scott, Kennedy David N, Pandya Deepak N

机构信息

Harvard Medical School Department of Psychiatry, Center for Morphometric Analysis, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, 02129, USA.

出版信息

Cereb Cortex. 2009 Apr;19(4):777-85. doi: 10.1093/cercor/bhn124. Epub 2008 Jul 31.

DOI:10.1093/cercor/bhn124
PMID:18669591
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2651473/
Abstract

Experimental and imaging studies in monkeys have outlined various long association fiber bundles within the temporoparietal region. In the present study the trajectory of the middle longitudinal fascicle (MdLF) has been delineated in 4 human subjects using diffusion tensor magnetic resonance imaging segmentation and tractography. The MdLF seems to extend from the inferior parietal lobule (IPL), specifically the angular gyrus, to the temporal pole remaining within the white matter of the superior temporal gyrus (STG). Comparison of the superior longitudinal fascicle II-arcuate fascicle (SLF II-AF) with the MdLF in the same subjects revealed that MdLF is located in a medial and caudal position relative to SLF II-AF and that it extends more rostrally. Given the location of MdLF between the IPL (angular gyrus) and the STG, it is suggested that MdLF could have a role in language and attention functions.

摘要

对猴子的实验和成像研究已经勾勒出颞顶叶区域内各种长联合纤维束。在本研究中,使用扩散张量磁共振成像分割和纤维束成像技术,在4名人类受试者中描绘了中间纵束(MdLF)的走行轨迹。MdLF似乎从顶下小叶(IPL),特别是角回,延伸至颞极,并保留在颞上回(STG)的白质内。在同一受试者中对上纵束II-弓状束(SLF II-AF)与MdLF进行比较发现,MdLF相对于SLF II-AF位于内侧和尾侧位置,并且其向更靠前的方向延伸。鉴于MdLF位于IPL(角回)和STG之间的位置,提示MdLF可能在语言和注意力功能中发挥作用。

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