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基于 MRI 的人类新皮质拓扑分区:一种具有可靠性估计的解剖指定方法。

MRI-Based Topographic Parcellation of Human Neocortex: An Anatomically Specified Method with Estimate of Reliability.

机构信息

Harvard Medical School, Boston, MA.

出版信息

J Cogn Neurosci. 1996 Nov;8(6):566-87. doi: 10.1162/jocn.1996.8.6.566.

DOI:10.1162/jocn.1996.8.6.566
PMID:23961985
Abstract

Abstract We describe a system of parcellation of the human neocortex, based upon magnetic resonance images, that conserves the topographic uniqueness of the individual brain. Subdivision of the neocortex, according to this system, is based entirely upon the configuration of a specified set of cerebral landmarks, principally neocortical fissures. These are present but unique in the details of their configurations in each individual brain. We introduce here a computer-assisted algorithm that ensures that a skilled investigator can execute the parcellation routine in a manageable period of time. Secondly, we outline a comprehensive set of conventions that specify how the boundaries of parcellation units are defined by anatomic landmarks. The average interobserver agreement in voxel assignment to parcellation units within the overall neocortex was 80.2%.

摘要

摘要 我们描述了一种基于磁共振成像的人类新皮质分区系统,该系统保留了个体大脑的拓扑独特性。根据该系统,新皮质的细分完全基于一组特定大脑地标(主要是新皮质裂)的配置。这些地标在每个个体大脑中的细节上是存在且唯一的。我们在这里引入了一种计算机辅助算法,以确保熟练的研究人员能够在可管理的时间内执行分区例程。其次,我们概述了一套全面的约定,规定了如何通过解剖学地标来定义分区单元的边界。在整个新皮质中,将体素分配给分区单元的观察者间平均一致性为 80.2%。

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