Schwerk W B, Görg C, Görg K, Richter G, Beckh K
Abt. Gastroenterologie und Stoffwechsel, Philipps-Universität Marburg.
Z Gastroenterol. 1991 Apr;29(4):146-52.
42 patients with solitary (n = 34) and multiple (n = 8) abscesses of the liver (n = 36) and the spleen (n = 6) were treated with ultrasound guided percutaneous interventions. 38 patients (90%) underwent a total of 97 closed abscess aspirations using needles of 0.9 and 1.3 mm in diameter. In 4 cases (10%) percutaneous catheter drainage was performed. Intravenous antibiotics were used in all cases. Those patients with closed abscess aspiration additionally received local injection of aminoglycosides into the cavity. 40 out of the 42 patients could be treated successfully by percutaneous methods for a cure rate of 95.2%. Percutaneous drainage failure occurred in 2.4%. One patient with multiple liver abscesses and catheter drainage died from myocardial infarction (hospital mortality 2.4%). Complications of ultrasound-guided interventions included two minor bleedings, requiring no therapy, and one pleural empyema (complication rate 7.1%). There were no treatment related lethal complications. These results indicate that abscesses of the liver and the spleen up to 10 cm in diameter can be effectively treated by closed (repetitive) needle aspiration and antibiotic therapy with a relatively low rate of complications. About half of our patients with abscesses of more than 10 cm received percutaneous catheter drainage. On the basis of our experience surgical drainage of liver abscesses and splenectomy in splenic abscesses should be restricted to those cases with percutaneous drainage failure.
42例肝(36例)和脾(6例)出现孤立性(34例)及多发性(8例)脓肿的患者接受了超声引导下经皮介入治疗。38例患者(90%)使用直径0.9毫米和1.3毫米的穿刺针共进行了97次闭合性脓肿穿刺抽吸。4例患者(10%)进行了经皮导管引流。所有病例均使用了静脉抗生素。那些接受闭合性脓肿穿刺抽吸的患者还额外接受了氨基糖苷类药物的腔内局部注射。42例患者中有40例通过经皮方法成功治愈,治愈率为95.2%。经皮引流失败率为2.4%。1例患有多发性肝脓肿且接受导管引流的患者死于心肌梗死(医院死亡率2.4%)。超声引导介入的并发症包括2例轻微出血,无需治疗,以及1例胸膜积脓(并发症发生率7.1%)。没有与治疗相关的致命并发症。这些结果表明,直径达10厘米的肝和脾脓肿可通过闭合性(重复)穿刺抽吸和抗生素治疗有效治疗,并发症发生率相对较低。我们约一半脓肿直径超过10厘米的患者接受了经皮导管引流。根据我们的经验,肝脓肿手术引流和脾脓肿脾切除术应仅限于经皮引流失败的病例。