Kon Yoshihiro, Yazawa Hideaki, Usui Yoko, Sato Kazuhiko
Research Institute for Innovation in Sustainable Chemistry, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba Central 5, Tsukuba, Ibaraki, 305-8565, Japan.
Chem Asian J. 2008 Sep 1;3(8-9):1642-8. doi: 10.1002/asia.200800156.
Environmentally benign oxidation of allylic alcohols by platinum black catalyst with aqueous hydrogen peroxide to give the corresponding alpha,beta-unsaturated carbonyl compounds in high yield is presented. Reactions are carried out under organic solvent- and halide-free conditions. The platinum black catalyst is commercially available and is found to be reusable at least seven times before significant loss of catalytic activity. The operation is very simple, even in a hectogram-scale synthesis, and gives corresponding carbonyl compounds in over 90 % yield. The effective oxidation of benzyl and secondary alcohols are also described.
本文介绍了在无有机溶剂和卤化物的条件下，使用铂黑催化剂和过氧化氢水溶液对烯丙醇进行环境友好型氧化反应，以高产率得到相应的α,β-不饱和羰基化合物。该铂黑催化剂可从市场购得，并且发现在催化活性显著降低之前至少可重复使用七次。该操作非常简单，即使在百克规模的合成中也是如此，并且能以超过90%的产率得到相应的羰基化合物。文中还描述了苄醇和仲醇的有效氧化反应。
