RIKEN Advanced Science Institute, Wako, Saitama 351-0198, Japan.
Org Lett. 2010 Oct 15;12(20):4540-3. doi: 10.1021/ol101839m.
A novel polymeric phosphotungstate catalyst bearing a poly(ethylene oxide-pyridinium) matrix was developed that efficiently promoted oxidation of a variety of alcohols, including highly sterically demanding neopentyl alcohols, with hydrogen peroxide, to afford the corresponding carbonyl compounds in up to quantitative yield. The chemoselective oxidation of sterically hindered secondary alcohols in the presence of primary alcohols was achieved. The catalyst could be reused four times without any loss of catalytic activity.
开发了一种新型的聚合物磷钨酸盐催化剂，其载体为聚（氧化乙烯-吡啶𬭩）基质，能够有效地促进各种醇（包括空间位阻要求较高的新戊醇）与过氧化氢的氧化反应，以高产率得到相应的羰基化合物。在伯醇存在下，能够实现空间位阻较大的仲醇的选择性氧化。催化剂重复使用四次后，仍保持催化活性，没有任何损失。
