Durand P, Bégin R, Samson L, Cantin A, Massé S, Dufresne A, Perreault G, Laflamme J
Institut de Recherche en Santé et Sécurité du Travail du Québec (IRSST), Montréal, Canada.
Am J Ind Med. 1991;20(1):37-47. doi: 10.1002/ajim.4700200104.
Interstitial lung disease and airflow limitation have been reported in silicon carbide workers but it is uncertain whether these recent observations reflect past working conditions alone (30 years ago) or both past and present conditions even if the latter have improved. To investigate this, we analyzed pairs of chest radiographs obtained in 1977 and 1984 in 128 silicon carbide plant workers. Three indices, related to density of small opacities, profusion of opacities, and presence of pleural plaques, were obtained. Student t-tests on results obtained in each time period showed the mean density (1.02 in 1977 and 0.56 in 1984) and profusion (4.27 in 1977 and 2.13 in 1984) indices to be significantly different. However, the pleural plaque index was not different in 1984 (0.34) as compared with 1977 (0.32). There was no deterioration of the radiographic image even in groups with density ratios equal or greater than 1/1. We concluded that the actual environmental working conditions did not influence the integrity of the lung radiographic image in these workers within a time span of 6 or 7 years.
据报道,碳化硅工人存在间质性肺病和气流受限的情况,但目前尚不确定这些近期观察结果是否仅反映过去(30年前)的工作条件,还是反映过去和现在的工作条件,即便后者已有改善。为了对此进行调查,我们分析了128名碳化硅工厂工人在1977年和1984年拍摄的成对胸部X光片。获得了与小阴影密度、阴影数量以及胸膜斑的存在相关的三项指标。对每个时间段获得的结果进行的学生t检验显示,平均密度指标(1977年为1.02,1984年为0.56)和阴影数量指标(1977年为4.27,1984年为2.13)存在显著差异。然而,胸膜斑指标在1984年(0.34)与1977年(0.32)相比并无差异。即使在密度比等于或大于1/1的组中,X光片影像也没有恶化。我们得出结论,在6至7年的时间跨度内,实际的工作环境条件并未影响这些工人肺部X光片影像的完整性。