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[吩噻嗪类药物所致的阴茎异常勃起]

[Priapism secondary to phenothiazines].

作者信息

Gómez Vegas A, Silmi Moyano A, Blázquez Izquierdo J, Corral Rosillo J, Delgado Martín J A, Gómez Ruiz J J, Prieto Chaparro L, Salinas Casado J

机构信息

Servicio de Urología, Hospital Universitario de San Carlos, Madrid, España.

出版信息

Arch Esp Urol. 1991 Apr;44(3):287-9.

PMID:1867509
Abstract

We report two cases of priapism in patients previously treated with neuroleptic agents. None of these patients had a previous history of urological or hematological disorders. These two patients warranted emergency treatment by punction-aspiration of the corpora cavernosa and posterior cavernospongiosa shunt. The foregoing approach achieved penile detumescence in both cases. Excellent results were achieved relative to erectile function in one patient. Although the mechanism responsible for phenothiazine-induce priapism has as yet not been elucidated, it has been suggested that this might be due to adrenergic block which directly inhibits the sympathetic impulse of detumescence.

摘要

我们报告了两例曾接受抗精神病药物治疗的患者发生阴茎异常勃起的病例。这些患者均无泌尿或血液系统疾病史。这两名患者均需通过阴茎海绵体穿刺抽吸和海绵体后分流进行紧急治疗。上述方法在两例患者中均实现了阴茎消肿。其中一名患者在勃起功能方面取得了优异的效果。尽管吩噻嗪诱导阴茎异常勃起的机制尚未阐明,但有人认为这可能是由于肾上腺素能阻滞直接抑制了消肿的交感冲动所致。

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