富含A、T的DNA的构象

Nucleic Acids Res. 1976 Oct;3(10):2443-50. doi: 10.1093/nar/3.10.2443.

DNAs from the genomes of Clostridium perfringens and Cytophaga johnsonii display orthodox A-DNA and B-DNA structures despite their high (A+L) nucleotide content. Unique structures, such as those found for synthetic DNAs having specific special sequences, do therefore not necessarily occur for DNAs having more random base sequence even if these have unusual base compositions. Clostridium perfringens DNA exhibits unusual structural properties only prior to purification by gel filtration.

尽管产气荚膜梭菌和约翰逊噬纤维菌基因组中的DNA具有较高的（A+T）核苷酸含量，但它们呈现出典型的A-DNA和B-DNA结构。因此，即使具有不寻常碱基组成的DNA碱基序列更为随机，也不一定会出现诸如具有特定特殊序列的合成DNA所具有的独特结构。产气荚膜梭菌DNA仅在通过凝胶过滤纯化之前表现出异常的结构特性。