Ross Lainie Friedman, Thistlethwaite J Richard
Pediatrics. 2008 Aug;122(2):454-61. doi: 10.1542/peds.2008-1525.
In the past half-century, solid-organ transplantation has become standard treatment for a variety of diseases in children and adults. The major limitation for all transplantation is the availability of donors, and the gap between demand and supply continues to grow despite the increase in living donors. Although rare, children do serve as living donors, and these donations raise serious ethical issues. This clinical report includes a discussion of the ethical considerations regarding minors serving as living donors, using the traditional benefit/burden calculus from the perspectives of both the donor and the recipient. The report also includes an examination of the circumstances under which a minor may morally participate as a living donor, how to minimize risks, and what the informed-consent process should entail. The American Academy of Pediatrics holds that minors can morally serve as living organ donors but only in exceptional circumstances when specific criteria are fulfilled.
在过去的半个世纪里,实体器官移植已成为治疗儿童和成人多种疾病的标准方法。所有移植的主要限制因素是供体的可获得性,尽管活体供体有所增加,但供需差距仍在不断扩大。虽然儿童作为活体供体的情况很少见,但这些捐赠引发了严重的伦理问题。本临床报告从供体和受体双方的角度,运用传统的利益/负担权衡法,讨论了未成年人作为活体供体的伦理考量。报告还探讨了未成年人在何种情况下可以在道德上作为活体供体参与捐赠、如何将风险降至最低以及知情同意程序应包含哪些内容。美国儿科学会认为,未成年人在道德上可以作为活体器官供体,但前提是仅在满足特定标准的特殊情况下。