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由一枚迁移至肺部的近距离放射治疗籽源所引起的放射性肺炎。

Radiation pneumonitis caused by a migrated brachytherapy seed lodged in the lung.

作者信息

Miura Noriyoshi, Kusuhara Yoshito, Numata Kousaku, Shirato Akitomi, Hashine Katsuyoshi, Sumiyoshi Yoshiteru, Kataoka Masaaki, Takechi Shinsuke

机构信息

Department of Urology, Shikoku Cancer Center, Ehime, Japan.

出版信息

Jpn J Clin Oncol. 2008 Sep;38(9):623-5. doi: 10.1093/jjco/hyn063. Epub 2008 Aug 2.

Abstract

We report a case of radiation pneumonitis caused by a migrated seed lodged in the lung after prostate brachytherapy. A 71-year-old man underwent transperineal interstitial permanent prostate brachytherapy for localized prostate cancer. On the day after brachytherapy, a routine postimplant chest X-ray revealed migration of one seed to the lower lobe of the left lung. After 1 month, pulmonary opacities were observed in the left lower lobe but not near the seed. He was diagnosed with bacterial pneumonia, and antibiotic therapy was commenced. Two months after brachytherapy, the patient's symptoms, laboratory data and pulmonary opacities improved; however, an abnormal shadow (consolidation) developed around the migrated seed. Lung consolidation disappeared almost completely 12 months after brachytherapy without any medical treatment. The abnormal shadow probably represented radiation pneumonitis. To the best of our knowledge, this is the first report of radiation pneumonitis caused by a migrated brachytherapy seed in the lung.

摘要

我们报告一例前列腺近距离放射治疗后,一枚迁移至肺部的放射粒子引发放射性肺炎的病例。一名71岁男性因局限性前列腺癌接受了经会阴间质永久性前列腺近距离放射治疗。近距离放射治疗后的次日,常规植入后胸部X线检查显示一枚放射粒子迁移至左肺下叶。1个月后,在左下叶观察到肺部混浊,但不在放射粒子附近。他被诊断为细菌性肺炎,并开始使用抗生素治疗。近距离放射治疗2个月后,患者的症状、实验室数据及肺部混浊有所改善;然而,在迁移的放射粒子周围出现了异常阴影(实变)。近距离放射治疗12个月后,肺部实变几乎完全消失,未进行任何医学治疗。该异常阴影可能代表放射性肺炎。据我们所知,这是肺部放射粒子迁移导致放射性肺炎的首例报告。

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