Mayer Gert
Division of Nephrology and Hypertensiology, Department of Internal Medicine IV, Innsbruck, Austria.
Wien Med Wochenschr. 2008;158(13-14):365-9. doi: 10.1007/s10354-008-0559-2.
The relationship between salt intake and blood pressure has been noteworthy for a long time. Nevertheless, the complex hemodynamic alterations associated with the salt-induced blood pressure changes have become clear only quite recently. Despite this knowledge, the concept of Guyton, which postulates that any increase in blood pressure should lead to a pressure natriuresis normalising blood pressure over the long term is still valid. As a conclusion, we have to remember that an elevation of arterial pressure can only be maintained if renal function as indicated by pressure natriuresis is impaired.
长期以来,盐摄入量与血压之间的关系一直备受关注。然而,与盐诱导的血压变化相关的复杂血流动力学改变直到最近才变得清晰。尽管有了这些认识,但盖顿的概念仍然有效,该概念假定任何血压升高最终都应导致压力性利钠作用使血压恢复正常。总之,我们必须记住,只有当压力性利钠作用所指示的肾功能受损时,动脉血压升高才能持续存在。