Jian Bo, Kimbrell Hillary Zalaznick, Sepulveda Antonia, Yu Gordon
Department of Pathology and Laboratory Medicine, Penn Presbyterian Medical Center, Philadelphia, Pennsylvania 19104, USA.
Diagn Cytopathol. 2008 Sep;36(9):662-5. doi: 10.1002/dc.20865.
Lymphoepithelial cyst (LEC) of the pancreas is a rare lesion. Here, we report three cases that we encountered during 2007 in our institution, which were evaluated by endosonography (EUS) and fine needle aspiration (FNA). All three patients were male with ages ranging from 47 to 77 years. Each patient had a single, cystic mass of the body/tail of the pancreas that was found incidentally on CT scan. The size of the masses ranged from 3 to 6.5 cm radiologically. For each patient, EUS showed a well-circumscribed, lobulated mass with smooth contours; the remainder of the pancreas appeared normal without ductal dilation. FNA of all three masses demonstrated predominantly anucleated squamous cells, amorphous keratinous debris, and lymphocytes. Cholesterol crystals were present in one case. One patient underwent surgical resection and the diagnosis of LEC was confirmed histologically. In conclusion, pancreatic LECs are extremely rare, benign cystic lesions. FNA study may help to render a correct diagnosis and reduce unnecessary surgery.
胰腺淋巴上皮囊肿（LEC）是一种罕见的病变。在此，我们报告2007年在我们机构遇到的三例病例，这些病例均通过内镜超声检查（EUS）和细针穿刺抽吸活检（FNA）进行评估。所有三名患者均为男性，年龄在47至77岁之间。每位患者胰腺体部/尾部均有一个单发的囊性肿块，均在CT扫描时偶然发现。影像学上肿块大小在3至6.5厘米之间。对于每位患者，EUS显示肿块边界清晰、呈分叶状，轮廓光滑；胰腺其余部分外观正常，无导管扩张。所有三个肿块的FNA主要显示无核鳞状细胞、无定形角质碎片和淋巴细胞。其中一例存在胆固醇结晶。一名患者接受了手术切除，组织学检查证实为LEC。总之，胰腺LEC极为罕见，是良性囊性病变。FNA检查可能有助于做出正确诊断并减少不必要的手术。
