Lei Dang, Rege Amol, Koti Manjunath, Smith Francis W, Wardlaw Douglas
School of Engineering, Mechanical Engineering, University of Birmingham, Birmingham, England.
J Spinal Disord Tech. 2008 Aug;21(6):430-5. doi: 10.1097/BSD.0b013e318153f7e4.
A new magnetic resonance imaging (MRI) classification of disc degeneration was correlated with discography. It was also studied for intraobserver and interobserver variability in interpreting disc abnormality and for the capability in predicting symptomatic disc.
To correlate the results of discography with a new MRI classification for disc degeneration and the presence of the vertebral endplate changes and the high intensity zone (HIZ).
MRI and discography have been compared in numerous studies as methods for detecting disc degeneration. The results were conflicting and the role of MRI in assessing discogenic pain remains ambiguous.
One hundred thirty-one discs in 55 patients were studied with pain provocation discography and MRI. A new MRI classification was correlated to discography and assessed together with the presence of end plate changes and HIZ, by the sensitivity and specificity in predicting a painful disc.
MRI classification had a good intra and interobserver agreement and a significant correlation with discographic findings. The sensitivity and specificity of MRI in predicting painful disc was 94% and 77%. The sensitivities and specificity of HIZs was 27% and 87% and for end plate changes was 32% and 98%, respectively.
Although MRI is an excellent investigation for assessing disc morphology it should be interpreted along with discography findings before planning fusion surgery. The proposed MRI classification is a useful aid in predicting painful degenerative disc. The utility of HIZs and end plate changes is limited due to low sensitivity.
一种新的椎间盘退变磁共振成像(MRI)分类方法与椎间盘造影术相关联。还研究了在解读椎间盘异常时观察者内和观察者间的变异性,以及预测有症状椎间盘的能力。
将椎间盘造影术的结果与一种新的用于椎间盘退变的MRI分类以及椎体终板改变和高强度区(HIZ)的存在情况相关联。
在众多研究中已对MRI和椎间盘造影术作为检测椎间盘退变的方法进行了比较。结果相互矛盾,MRI在评估椎间盘源性疼痛中的作用仍不明确。
对55例患者的131个椎间盘进行了疼痛激发椎间盘造影术和MRI研究。一种新的MRI分类与椎间盘造影术相关联,并通过预测疼痛性椎间盘的敏感性和特异性,与终板改变和HIZ的存在情况一起进行评估。
MRI分类在观察者内和观察者间具有良好的一致性,且与椎间盘造影结果有显著相关性。MRI预测疼痛性椎间盘的敏感性和特异性分别为94%和77%。HIZ的敏感性和特异性分别为27%和87%,终板改变的敏感性和特异性分别为32%和98%。
尽管MRI是评估椎间盘形态的优秀检查方法,但在计划融合手术前,应结合椎间盘造影结果进行解读。所提出的MRI分类在预测疼痛性退变椎间盘方面是一种有用的辅助方法。由于敏感性较低,HIZ和终板改变的实用性有限。