Clemedson C
Expertrådet AB, Sollentuna, Sweden.
Clin Pharmacol Ther. 2008 Aug;84(2):200-2. doi: 10.1038/clpt.2008.135.
ACuteTox (optimization and prevalidation of an in vitro test strategy for predicting human acute toxicity) is an integrated European Union project under the Sixth Framework Programme with the aim of demonstrating that animal tests for acute systemic toxicity currently used for regulatory purposes could be replaced by a combination of alternative assays. Validated alternative test methods are urgently required for safety toxicology testing of chemicals, cosmetics, and drugs.
急性毒性试验（预测人类急性毒性体外试验策略的优化与预验证）是欧盟第六框架计划下的一个综合项目，旨在证明目前用于监管目的的急性全身毒性动物试验可以用一系列替代试验组合来取代。化学品、化妆品和药品的安全毒理学检测迫切需要经过验证的替代试验方法。
