Tyler Heather L, Triplett Eric W
Department of Microbiology and Cell Science, University of Florida, Gainesville, Florida 32611-0700, USA.
Annu Rev Phytopathol. 2008;46:53-73. doi: 10.1146/annurev.phyto.011708.103102.
Non-plant pathogenic endophytic bacteria can promote plant growth, improve nitrogen nutrition, and, in some cases, are human pathogens. Recent work in several laboratories has shown that enteric bacteria are common inhabitants of the interior of plants. These observations led to the experiments that showed the entry into plants of enteric human pathogens such as Salmonella and E. coli O157:H7. The extent of endophytic colonization by strains is regulated by plant defenses and several genetic determinants necessary for this interior colonization in endophytic bacteria have been identified. The genomes of four endophytic bacteria now available should promote discovery of other genes that contribute to this phenotype. Common virulence factors in plant and animal pathogens have also been described in bacteria that can infect both plant and animal models. Future directions in all of these areas are proposed.
非植物病原内生细菌可促进植物生长、改善氮素营养，且在某些情况下还是人类病原体。多个实验室最近的研究表明，肠道细菌是植物内部的常见栖居者。这些观察结果引发了相关实验，实验显示肠道人类病原体如沙门氏菌和大肠杆菌O157:H7可进入植物。菌株的内生定殖程度受植物防御机制调控，并且已经鉴定出内生细菌在植物内部定殖所必需的几个遗传决定因素。目前已有的四种内生细菌基因组应有助于发现其他导致这种表型的基因。在可感染植物和动物模型的细菌中，也描述了植物和动物病原体中的常见毒力因子。本文还提出了所有这些领域的未来研究方向。
