Dalal Anand A, Stanford Richard, Henry Henk, Borah Bijan
GlaxoSmithKline, Research Triangle Park, North Carolina, USA.
Ann Allergy Asthma Immunol. 2008 Jul;101(1):23-9. doi: 10.1016/S1081-1206(10)60830-7.
Little is known about the specific cost effect of rhinitis on third-party payers. No recently reported studies have examined the economic burden of rhinitis in managed care. Furthermore, the direct costs of chronic rhinitis have not been evaluated and potential differences in health care use and costs of allergic rhinitis have not been examined.
To evaluate the economic burden of allergic rhinitis and chronic rhinitis to third-party payers in a large US managed care plan.
In a retrospective analysis using pharmacy and medical claims data from a US health plan covering approximately 15 million members, health care use and cost data were summarized for patients with allergic or chronic rhinitis (n = 301,001) for the 13-month study period (January 1, 2004, to January 31, 2005).
Average rhinitis-related total costs were $657 per patient each year ($319 in medical costs and $338 in pharmacy costs). Ambulatory visits were the primary contributor to rhinitis-related medical costs. Antihistamines were the most common rhinitis medication, followed by intranasal corticosteroids (INSs) and montelukast. Many patients (37% with at least 1 filled prescription for an antihistamine, an INS, or montelukast) used combination therapy. Of the 3 main pharmacotherapy categories, montelukast was associated with the highest pharmacy cost ($353 vs $198 for antihistamines and $231 for INSs per patient each year for monotherapy) and drove the average annual cost of combination therapy regardless of the concomitant medication(s). The most common comorbidities were sinusitis and asthma, present in 51.1% and 27.9% of patients, respectively. Comorbidities increased rhinitis-related health care costs.
Allergic rhinitis and chronic rhinitis imposed a significant financial burden on third-party payers in a large US managed care plan. The presence of comorbidities further increased the rhinitis-related treatment costs.
关于鼻炎对第三方支付方的具体成本影响,人们了解甚少。近期没有报告研究过管理式医疗中鼻炎的经济负担。此外,慢性鼻炎的直接成本尚未得到评估,过敏性鼻炎在医疗保健使用和成本方面的潜在差异也未得到研究。
评估在美国一个大型管理式医疗计划中,过敏性鼻炎和慢性鼻炎给第三方支付方带来的经济负担。
在一项回顾性分析中,使用来自美国一个覆盖约1500万成员的健康计划的药房和医疗理赔数据,汇总了13个月研究期(2004年1月1日至2005年1月31日)内过敏性或慢性鼻炎患者(n = 301,001)的医疗保健使用和成本数据。
每位患者每年与鼻炎相关的平均总成本为657美元(医疗成本319美元,药房成本338美元)。门诊就诊是与鼻炎相关医疗成本的主要构成部分。抗组胺药是最常用的鼻炎药物,其次是鼻用糖皮质激素(INSs)和孟鲁司特。许多患者(37%至少有1次抗组胺药、INS或孟鲁司特的处方配药记录)使用联合治疗。在3种主要药物治疗类别中,孟鲁司特的药房成本最高(单药治疗时每位患者每年为353美元,抗组胺药为198美元,INSs为231美元),并且无论联合使用何种药物,它都推动了联合治疗的年均成本。最常见的合并症是鼻窦炎和哮喘,分别出现在51.1%和27.9%的患者中。合并症增加了与鼻炎相关的医疗保健成本。
在美国一个大型管理式医疗计划中,过敏性鼻炎和慢性鼻炎给第三方支付方带来了巨大的经济负担。合并症的存在进一步增加了与鼻炎相关的治疗成本。