Catalano Orlando, Aiani Luca, Barozzi Libero, Bokor Daniela, De Marchi Armanda, Faletti Carlo, Maggioni Fabio, Montanari Nicola, Orlandi Paolo Emilio, Siani Alfredo, Sidhu Paul S, Thompson Peter K, Valentino Massimo, Ziosi Angelo, Martegani Alberto
Department of Radiology, I.N.T. Pascale, via Semmola, 80131, Naples, Italy.
Abdom Imaging. 2009 Mar-Apr;34(2):225-34. doi: 10.1007/s00261-008-9452-0.
The objective of this study was to evaluate the concordance of US and contrast-enhanced US (CEUS) with CT in the assessment of solid organ injury following blunt trauma. Patients underwent complete US examination, including free fluid search and solid organ analysis. CEUS followed, using low-mechanical index techniques and SonoVue. CT was performed within 1 h. Among 156 enrolled patients, 91 had one or more abnormalities (n = 107) at CT: 26 renal, 38 liver, 43 spleen. Sensitivity, specificity, and accuracy for renal trauma at baseline US were 36%, 98%, and 88%, respectively, after CEUS values increased to 69%, 99%, and 94%. For liver baseline US values were 68%, 97%, and 90%; after CEUS were 84%, 99%, and 96%. For spleen, results were 77%, 96%, and 91% at baseline US and 93%, 99%, and 97% after CEUS. Per patient evaluation gave the following results in terms of sensitivity, specificity and accuracy: 79%, 82%, 80% at baseline US; 94%, 89%, and 92% following CEUS. CEUS is more sensitive than US in the detection of solid organ injury, potentially reducing the need for further imaging. False negatives from CEUS are due to minor injuries, without relevant consequences for patient management and prognosis.
本研究的目的是评估超声(US)及超声造影(CEUS)与CT在评估钝性创伤后实体器官损伤方面的一致性。患者接受了完整的超声检查,包括游离液体探查和实体器官分析。随后采用低机械指数技术和声诺维进行CEUS检查。CT在1小时内完成。在156例入组患者中,91例在CT检查时有一处或多处异常(共107处):26处肾脏损伤、38处肝脏损伤、43处脾脏损伤。基线超声检查对肾损伤的敏感性、特异性和准确性分别为36%、98%和88%,CEUS检查后分别增至69%、99%和94%。肝脏损伤基线超声检查的相应数值为68%、97%和90%;CEUS检查后为84%、99%和96%。脾脏损伤基线超声检查结果为77%、96%和91%,CEUS检查后为93%、99%和97%。按患者评估,基线超声检查的敏感性、特异性和准确性结果如下:79%、82%、80%;CEUS检查后为94%、89%和92%。在检测实体器官损伤方面,CEUS比超声更敏感,可能会减少进一步影像学检查的需求。CEUS的假阴性是由轻伤所致,对患者的治疗和预后无相关影响。