Esatgil M U, Gülanber A, Aydin H
Department of Parasitology, Faculty of Veterinary Medicine, Istanbul University, Istanbul, Turkey.
Pol J Vet Sci. 2008;11(2):143-5.
The present study investigated the efficacy of topical selamectin for elimination of naturally acquired Trichosomoides crassicauda infection in rats. Twelve T. crassicauda-positive rats were assigned to the treatment group and six rats were assigned to the control group. Selamectin (6 mg/kg) was applied topically to the skin in a single spot at the base of the neck in front of the scapulae in the treatment group. To assess the efficacy of the treatment, animal faeces were investigated with the use of the flotation technique on days 0, 4, 14 and 24 after selamectin application. The rats of the treatment and control groups were necropsied on the day 24. In the treatment group, 7 of 12 infected rats were cured completely. Topical selamectin was found to be effective in eliminating T. crassicauda infection in rats.
本研究调查了局部应用塞拉菌素对消除大鼠自然感染的粗尾毛首线虫的疗效。将12只粗尾毛首线虫阳性大鼠分配到治疗组，6只大鼠分配到对照组。治疗组在肩胛前方颈部基部的单个部位将塞拉菌素（6mg/kg）局部应用于皮肤。为评估治疗效果，在应用塞拉菌素后的第0、4、14和24天，使用浮选技术对动物粪便进行检查。治疗组和对照组的大鼠在第24天进行尸检。在治疗组中，12只感染大鼠中有7只完全治愈。发现局部应用塞拉菌素对消除大鼠粗尾毛首线虫感染有效。
