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小儿肾结石病的经皮肾镜取石术:5年的本地经验

Percutaneous nephrolithotomy for pediatric renal calculus disease: 5 years of local experience.

作者信息

Romanowsky Igor, Lismer Leonard, Asali Murad, Rosenberg Eran, Kaneti Jackob

机构信息

Department of Urology, Soroka University Medical Center, Beer-Sheva, Israel.

出版信息

Arch Ital Urol Androl. 2008 Jun;80(2):56-8.

Abstract

INTRODUCTION

Pediatric renal calculus disease has been considered a management dilemma. The various treatment modalities have different effects on the growing kidney, with concern to the significant recurrence rate, and the long-term outcome. We report our experience with performing percutaneous nephrolithotomy (PCNL) monotherapy in staghorn or complex pediatric renal calculi.

PATIENTS AND METHODS

We retrospectively analyzed the results of PCNL in 9 children treated at our institute between 2001 and 2006. A total of 9 children (10 renal units) with a mean age of 10.1 years underwent 10 percutaneous nephrolithotomies (PCNLs). One patient underwent bilateral percutaneous nephrolithotomy at the initial presentation. The average calculus size was 45.9 mm (range 15-65 mm). Of the patients, 7 had complete or partial staghorn, 1 was a shock wave lithotripsy (SWL) failure, and 1 had a stone located in a lower calyx with a narrowed infundibulum; 7 from the 9 patients turned out to have some kind of a metabolic disorder--cystinuria in 6 patients and hyperoxaluria in one patient. The operations were performed under the guidance of monoplane fluoroscopy--standard PCNL in 3 cases and percutaneous nephrolithotomy with minimal access (mini-perc) in 7 cases. A rigid nephroscope was used in all of the cases. The stones were fragmented with pneumatic or ultrasonic devices and extracted with forceps.

RESULTS

Stone-free status was achieved in 8 renal units (80%) after a single stage PCNL. With subsequent shock wave lithotripsy (SWL), the clearance rate had increased to 100%. The mean operating time was 88 minutes (range, 35 to 180 minutes) and no intraoperative or postoperative major complications were observed and no blood transfusions were required. One patient had suffered from intraoperative hypothermia, which had responded to conservative treatment.

CONCLUSIONS

PCNL is an effective and safe form of therapy in pediatric stone disease. Since two-thirds of pediatric stone patients have an underlying metabolic disorder, a close cooperation of adult and pediatric urologists, nephrologists and radiologists is necessary in order to achieve good results in the treatment of pediatric nephrolithiasis.

摘要

引言

小儿肾结石病一直被视为治疗难题。各种治疗方式对发育中的肾脏有不同影响,同时存在显著的复发率和长期预后问题。我们报告了在鹿角形或复杂性小儿肾结石中采用经皮肾镜取石术(PCNL)单一疗法的经验。

患者与方法

我们回顾性分析了2001年至2006年在我院接受治疗的9例儿童PCNL的结果。共有9例儿童(10个肾单位),平均年龄10.1岁,接受了10次经皮肾镜取石术(PCNL)。1例患者在初次就诊时接受了双侧经皮肾镜取石术。结石平均大小为45.9毫米(范围为15 - 65毫米)。其中,7例有完全或部分鹿角形结石,1例是体外冲击波碎石术(SWL)失败者,1例结石位于下盏且漏斗部狭窄;9例患者中有7例存在某种代谢紊乱——6例为胱氨酸尿症,1例为高草酸尿症。手术在单平面荧光透视引导下进行——3例采用标准PCNL,7例采用微创经皮肾镜取石术(mini - perc)。所有病例均使用硬性肾镜。结石用气动或超声设备破碎,并用钳子取出。

结果

一期PCNL后,8个肾单位(80%)达到无结石状态。随后进行体外冲击波碎石术(SWL),清除率提高到100%。平均手术时间为88分钟(范围为35至180分钟),未观察到术中或术后严重并发症,也无需输血。1例患者术中出现体温过低,经保守治疗后好转。

结论

PCNL是小儿结石病一种有效且安全的治疗方式。由于三分之二的小儿结石患者存在潜在的代谢紊乱,成人和小儿泌尿外科医生、肾内科医生及放射科医生密切合作对于小儿肾结石的治疗取得良好效果是必要的。

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