Pulay Attila J, Dawson Deborah A, Ruan W June, Pickering Roger P, Huang Boji, Chou S Patricia, Grant Bridget F
Laboratory of Epidemiology and Biometry, Division of Intramural Clinical and Biological Research, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health/DHHS, 5635 Fishers Lane, Bethesda, MD 20892, USA.
J Pers Disord. 2008 Aug;22(4):405-17. doi: 10.1521/pedi.2008.22.4.405.
The present study examined one dimensional approach to personality disorders (PDs) in a large (n = 43,093), nationally representative sample of the U.S. population. Respondents were classified in four personality severity categories (no PD, subthreshold PD, simple PD, complex PD). Linear regression analyses were conducted to examine mental disability by PD severity for major DSM-IV substance use, mood and anxiety disorders. Significant increases in disability were observed between no PD and simple PD and between simple PD and complex PD for each Axis I disorder except drug dependence, but few differences in disability were found between no PD and subthreshold PD. This study found support for the clinical utility of the dimensional classification of PD severity with regard to the distinction between simple and complex PD and for a combined no PD-subthreshold PD level of severity. Future planned analyses will address the clinical utility of the classification prospectively, with a full battery of all Axis II PDs.
本研究在美国人口的一个具有全国代表性的大样本(n = 43,093)中检验了人格障碍(PD)的一维方法。受访者被分为四种人格严重程度类别(无PD、阈下PD、单纯PD、复杂PD)。进行线性回归分析,以研究主要DSM-IV物质使用障碍、情绪障碍和焦虑障碍的PD严重程度与精神残疾之间的关系。除药物依赖外,每种轴I障碍在无PD与单纯PD之间以及单纯PD与复杂PD之间均观察到残疾显著增加,但在无PD与阈下PD之间未发现残疾差异。本研究支持PD严重程度维度分类在区分单纯PD和复杂PD方面的临床实用性,以及支持无PD-阈下PD联合严重程度水平。未来计划的分析将前瞻性地探讨该分类的临床实用性,并纳入所有轴II PD的完整量表。