Avari Jennifer N, Rhee Edward K
Pediatric Cardiology, Washington University School of Medicine/St. Louis Children's Hospital, St. Louis, Missouri, USA.
Pacing Clin Electrophysiol. 2008 Aug;31(8):968-73. doi: 10.1111/j.1540-8159.2008.01123.x.
Coronary sinus accessory pathways (CSAPs), atrioventricular connections formed by the coronary sinus myocardial coat, have been described in adult patients, but not systematically described in pediatric patients.
Patients who underwent CSAP ablation were compared to patients with right posteroseptal (RPS) pathway ablation (control group) from November 2004 to June 2007. Retrospective reviews of preablation 12-lead electrocardiogram (EKG), fluoroscopic, and intracardiac electrogram data were then performed to identify electrophysiologic markers of CSAP.
A total of 23 patients were identified: 13 with CSAP and 10 with RPS pathways. Preablation EKGs demonstrated preexcitation in 8/10 (80%) patients with RPS pathways versus 9/13 (69%) patients with CSAP (P = 0.66). Preexcitation with a negative delta wave in lead II was seen in 5/9 (56%) patients with CSAP versus 0/8 in RPS (P = 0.029), and preexcitation with a positive delta wave in augmented vector right (aVR) was seen in 9/9 (100%) patients with CSAP versus 3/8 (37.5%) with RPS (P = 0.009). Accessory pathway (AP) potentials were seen on the coronary sinus (CS) catheter in 6/13 (46%) of CSAP and in 0 RPS ablations (P = 0.019). Recurrence of tachycardia occurred in 5/13 (38%) of patients with CSAP and 1/10 (10%) of patients with RPS pathways (P = 0.18).
CSAPs should be considered when preablation EKG demonstrates preexcitation with a negative delta wave in lead II and a positive delta wave in aVR, and if an AP potential is seen on the CS catheter. Recurrence of tachycardia postablation or the need for multiple ablations should raise suspicion for a CSAP.
冠状窦旁道(CSAPs)是由冠状窦心肌外层形成的房室连接,已在成年患者中有所描述,但在儿科患者中尚未进行系统描述。
将2004年11月至2007年6月期间接受CSAP消融的患者与右后间隔(RPS)旁道消融患者(对照组)进行比较。然后对消融前12导联心电图(EKG)、荧光透视和心内电图数据进行回顾性分析,以确定CSAP的电生理标志物。
共确定23例患者:13例为CSAP,10例为RPS旁道。消融前EKG显示,10例RPS旁道患者中有8例(80%)存在预激,而13例CSAP患者中有9例(69%)存在预激(P = 0.66)。II导联负向δ波预激在9例CSAP患者中有5例(56%)出现,而RPS患者中8例均未出现(P = 0.029);右心前区增强导联(aVR)正向δ波预激在9例CSAP患者中全部出现(100%),而RPS患者中8例有3例(37.5%)出现(P = 0.009)。CSAP患者中有6/13(46%)在冠状窦(CS)导管上可见旁道(AP)电位,而RPS消融患者中均未出现(P = 0.019)。CSAP患者中有5/13(38%)出现心动过速复发,RPS旁道患者中有1/10(10%)出现心动过速复发(P = 0.18)。
当消融前EKG显示II导联负向δ波预激和aVR正向δ波预激,且CS导管上可见AP电位时,应考虑CSAP。消融后心动过速复发或需要多次消融时,应怀疑CSAP。