MacKay R J
Department of Large Animal Clinical Sciences, University of Florida, Gainesville, Florida, USA.
Equine Vet J. 2008 Jul;40(5):518-20. doi: 10.2746/042516408X322409.
The aim of the current study was to quantify sweating responses to intradermal terbutaline in normal horses. Seven Thoroughbred horses were used. Terbutaline (10-fold dilutions from 1000-0.001 mg/l) and a saline control were injected intradermally (0.1 ml/site) and sweat collected for 30 min into absorbent pads taped over each injection site. Tests were performed monthly for 11 successive months and temperature, relative humidity and dewpoint were measured at the time of testing. There was no significant effect (P<or=0.05) of environmental variables or time of year on sweat responses at any dose. There was significant effect (P<0.001) of terbutaline concentration on sweat weight, with significant increases at every concentration from 0.1-1000 mg/l. This quantitative intradermal terbutaline sweat test should be a useful aid to the study of equine sweating and anhidrosis.
本研究的目的是量化正常马匹对皮内注射特布他林的出汗反应。使用了7匹纯种马。将特布他林（浓度从1000 - 0.001 mg/l进行10倍稀释）和生理盐水对照皮内注射（0.1 ml/部位），并在每个注射部位用胶带粘贴吸收垫收集30分钟的汗液。连续11个月每月进行一次测试，并在测试时测量温度、相对湿度和露点。在任何剂量下，环境变量或一年中的时间对出汗反应均无显著影响（P≤0.05）。特布他林浓度对汗液重量有显著影响（P<0.001），从0.1 - 1000 mg/l的每个浓度下汗液重量均显著增加。这种定量皮内特布他林出汗试验应该有助于马出汗和无汗症的研究。
