Collard Harold R, Pantilat Steven Z
Department of Medicine, University of California San Francisco, San Francisco, California 94143, USA.
Curr Opin Support Palliat Care. 2008 Jun;2(2):100-4. doi: 10.1097/SPC.0b013e3282ff6336.
Dyspnea is a common complication of interstitial lung disease, yet little is known about its cause and effective management. This review attempts to summarize the current state of the art in this area.
Dyspnea is a near-universal finding in people with interstitial lung disease, predominantly due to neuromechanical abnormalities. Several well studied metrics exist for the measurement of dyspnea in this population, and its severity has been linked to quality of life and survival. The management of dyspnea in interstitial lung disease remains a challenge, with no proven pharmacological options. Pulmonary rehabilitation shows therapeutic promise, and aggressive treatment of physical and psychiatric comorbidities is important.
Dyspnea remains a common and difficult to treat symptom for people with interstitial lung disease. More research is sorely needed.
呼吸困难是间质性肺疾病的常见并发症，但其病因及有效管理方法却鲜为人知。本综述旨在总结该领域的当前技术水平。
呼吸困难在间质性肺疾病患者中几乎普遍存在，主要是由于神经机械异常。针对该人群呼吸困难的测量有几种经过充分研究的指标，其严重程度与生活质量和生存率相关。间质性肺疾病中呼吸困难的管理仍然是一项挑战，尚无经证实的药物治疗选择。肺康复显示出治疗前景，积极治疗身体和精神合并症很重要。
呼吸困难仍然是间质性肺疾病患者常见且难以治疗的症状。迫切需要更多研究。
