Wu Ying, Xu Hui-Ming, Zhang Song-Ying, Xu Wei-Hai, Tang Feng, Yang Li-Hong
Zhejiang Family Planning Institute, Hangzhou, Zhejiang 310012, China.
Zhonghua Nan Ke Xue. 2008 Jul;14(7):610-3.
To determine the correlation of the rate of morphologically normal sperm, sperm head defect, teratozoosperm index (TZI) and sperm deformity index (SDI) with the fertilization outcome of IVF and intracytoplasmic sperm injection (ICSI).
We detected normal sperm morphology, sperm head defect, TZI and SDI by Krüger's strict criteria and compared them with the rate of fertilization.
In either IVF or ICSI, the fertilization rate did not show any correlation with the normal sperm morphology rate, the head defect rate, TZI and SDI, nor any statistic differences were found in the rates of fertilization, clinical pregnancy and quality embryos either between the SDI > 1.6 and the SDI < 1.6 groups (P > 0.05) or between the normal sperm morphology rate > 15% and < 15% groups (P > 0.05).
Sperm morphology has no predictive value for the rate of fertilization in vitro.
确定形态正常精子率、精子头部缺陷、畸形精子指数(TZI)和精子畸形指数(SDI)与体外受精(IVF)和卵胞浆内单精子注射(ICSI)受精结局的相关性。
我们采用克鲁格严格标准检测正常精子形态、精子头部缺陷、TZI和SDI,并将其与受精率进行比较。
在IVF或ICSI中,受精率与正常精子形态率、头部缺陷率、TZI和SDI均无相关性,SDI>1.6组与SDI<1.6组之间以及正常精子形态率>15%与<15%组之间,受精率、临床妊娠率和优质胚胎率均无统计学差异(P>0.05)。
精子形态对体外受精率无预测价值。