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认知功能障碍、尿潴留以及丘脑病变——警惕可能的中枢神经系统弓蛔虫病。

Cognitive dysfunction, urinary retention, and a lesion in the thalamus--beware of possible toxocariasis of the central nervous system.

作者信息

Scheid Rainer, Tina Jentzsch R, Schroeter Matthias L

机构信息

Day Clinic of Cognitive Neurology, University of Leipzig, Germany.

出版信息

Clin Neurol Neurosurg. 2008 Dec;110(10):1054-7. doi: 10.1016/j.clineuro.2008.06.014. Epub 2008 Aug 8.

Abstract

Toxocariasis of the central nervous system is usually characterized by an eosinophilic meningitis, encephalitis or myelitis. We here report a patient with an at least 7 years history of unexplained neurologic signs and symptoms. MRI showed a cystic lesion in the left thalamus, compatible with a parasitic infection. Blood and CSF analyses were positive for Toxocara canis IgG Western-blot, but were otherwise unremarkable. The case report raises the question whether there are chronic or late variants of this disease.

摘要

中枢神经系统弓蛔虫病通常表现为嗜酸性脑膜炎、脑炎或脊髓炎。我们在此报告一名患者,其具有至少7年无法解释的神经体征和症状病史。磁共振成像(MRI)显示左侧丘脑有一个囊性病变,符合寄生虫感染表现。血液和脑脊液分析显示犬弓蛔虫IgG免疫印迹试验呈阳性,但其他方面无异常。该病例报告提出了一个问题,即这种疾病是否存在慢性或晚期变体。

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