Hamidou M A, Gueglio B, Cassagneau E, Trewick D, Grolleau J Y
Département de Médecine Interne, Hotel-Dieu University Hospital, Nantes, France.
J Rheumatol. 1999 Feb;26(2):443-5.
We describe a case of Henoch-Schönlein purpura in the onset of Toxocara canis infection. The diagnosis was made in a 17-year-old boy based on the association of palpable purpura, oligoarthritis, acute abdominal pain, microhematuria, and cutaneous vasculitis. Toxocariasis, suggested by hypereosinophilia and domestic contact with a puppy, was confirmed by anti-Toxocara IgG and IgE and Western blot. Complete spontaneous resolution occurred within a few days. Transient presence of antinuclear antibodies and the absence of larvae in the skin biopsy favor an immunologic parasite induced disorder. A hypersensitivity vasculitis to Toxocara canis is suggested.
我们描述了一例犬弓首蛔虫感染初期出现的过敏性紫癜病例。该诊断是在一名17岁男孩身上做出的,依据为可触及的紫癜、少关节炎、急性腹痛、微量血尿和皮肤血管炎。嗜酸性粒细胞增多以及与一只幼犬的家庭接触提示了弓首蛔虫病,抗犬弓首蛔虫IgG和IgE以及免疫印迹法证实了该病。数天内完全自发缓解。皮肤活检中抗核抗体的短暂出现以及未发现幼虫支持免疫性寄生虫诱导的疾病。提示为对犬弓首蛔虫的超敏性血管炎。