青少年医疗服务提供者是否愿意向青少年推荐用于尼古丁成瘾和肺癌风险的遗传易感性检测。
Adolescent medical providers' willingness to recommend genetic susceptibility testing for nicotine addiction and lung cancer risk to adolescents.
机构信息
Cancer Control Program, Lombardi Comprehensive Cancer Center, Washington DC 20007, USA.
出版信息
J Pediatr Psychol. 2009 Jul;34(6):617-26. doi: 10.1093/jpepsy/jsn086. Epub 2008 Aug 7.
OBJECTIVE
To examine the influences of disease, lifestyle, and other factors on adolescent medical providers' willingness to recommend genetic susceptibility testing (GST).
METHOD
Providers attending a national conference completed a self-report survey (n = 232) about their willingness to recommend hypothetical GSTs, differentiated by disease (nicotine addiction/lung cancer), patient lifestyle (nonsmoker/smoker), and other contextual factors.
RESULTS
Compared to recommending GST unconditionally, providers were more willing to recommend GST with parental/patient consent/assent, and in the presence of a preexisting illness and substance abuse history. Compared to offering nicotine addiction GST to a nonsmoker, providers were more willing to offer this type of testing to a smoker and were more willing to offer GST for lung cancer regardless of patient lifestyle.
CONCLUSIONS
Providers' willingness to recommend GSTs is sensitive to many factors. Efforts to integrate GST into adolescent preventive care likely will need to address these and other influences on provider behavior.
目的
探讨疾病、生活方式和其他因素对青少年医疗服务提供者推荐遗传易感性检测（GST）意愿的影响。
方法
参加全国性会议的提供者完成了一份关于他们推荐假设 GST 的意愿的自我报告调查（n=232），根据疾病（尼古丁成瘾/肺癌）、患者生活方式（不吸烟者/吸烟者）和其他背景因素进行了区分。
结果
与无条件推荐 GST 相比，提供者更愿意在获得父母/患者同意/同意的情况下，以及在存在先前存在的疾病和药物滥用史的情况下推荐 GST。与向不吸烟者提供尼古丁成瘾 GST 相比，提供者更愿意向吸烟者提供这种类型的检测，并且无论患者的生活方式如何，都更愿意提供肺癌 GST。
结论
提供者推荐 GST 的意愿对许多因素敏感。将 GST 纳入青少年预防保健工作可能需要解决这些因素以及对提供者行为的其他影响。
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