正交连接：一种由肽核酸-肽-肽核酸缀合物组成的三件式组件。
Orthogonal ligation: a three piece assembly of a PNA-peptide-PNA conjugate.
作者信息
Burlina Fabienne, Dixson David D, Doyle Robert P, Chassaing Gérard, Boddy Christopher N, Dawson Philip, Offer John
机构信息
UPMC Univ Paris 06, CNRS UMR 7613, 4 place Jussieu, F-75005 Paris, France.
出版信息
Chem Commun (Camb). 2008 Jun 28(24):2785-7. doi: 10.1039/b801242c. Epub 2008 Apr 14.
DOI:10.1039/b801242c
PMID:18688310
Abstract
A PNA-peptide-PNA conjugate was assembled from three fragments using a combination of native chemical ligation and an orthogonal, auxiliary-mediated ligation.
摘要
一种肽核酸-肽-肽核酸缀合物是通过天然化学连接和一种正交的、辅助介导的连接相结合的方式，由三个片段组装而成。
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