Bobić B, Nikolić A, Klun I, Vujanić M, Djurković-Djaković O
Belgrade University Institute for Medical Research, Toxoplasmosis Research Laboratory, Belgrade, Serbia.
Parassitologia. 2007 Dec;49(4):227-30.
Toxoplasma gondii infection prevalence and infection risk factors were analyzed in a series of 765 women of generative age from throughout Serbia tested at the Institute for Medical Research Toxoplasmosis Laboratory between 2001 and 2005. The infection risk factors were additionally analyzed in a group of 53 women with acute infection (cases) compared to a group of seronegative women matched for age and education level (controls). The overall prevalence of infection was 33%. Infection risk factors in the whole series were undercooked meat consumption (RR = 1.77, 95% CI = 1.16-2.7, P = 0.008) and exposure to soil (RR = 1.63, 95% CI = 1.17-2.29, P = 0.004), particularly in less educated women. Moreover, undercooked meat consumption was the single predictor of infection in women with acute infection, with an 11-fold increased risk of infection in women who acknowledged consumption of undercooked meat (RR = 11.21, 95% CI = 3.10-40.53, P = 0.000). These data prompted us to analyze the significance of consumption of particular meat types as sources of infection. Of all the meat types mostly consumed in Serbia, only consumption of beef (RR = 1.006, 95% CI = 1.001-1.011, P = 0.027) was shown to influence Toxoplasma infection rates.
2001年至2005年期间，在塞尔维亚医学研究所弓形虫病实验室对来自塞尔维亚各地的765名育龄妇女进行了检测，分析了弓形虫感染率及感染风险因素。另外，将一组53名急性感染女性（病例组）与一组年龄和教育水平相匹配的血清阴性女性（对照组）进行比较，分析感染风险因素。总体感染率为33%。整个系列中的感染风险因素包括食用未煮熟的肉类（相对危险度=1.77，95%可信区间=1.16-2.7，P=0.008）和接触土壤（相对危险度=1.63，95%可信区间=1.17-2.29，P=0.004），在受教育程度较低的女性中尤为明显。此外，食用未煮熟的肉类是急性感染女性感染的唯一预测因素，承认食用未煮熟肉类的女性感染风险增加11倍（相对危险度=11.21，95%可信区间=3.10-40.53，P=0.000）。这些数据促使我们分析特定肉类类型作为感染源的食用意义。在塞尔维亚最常食用的所有肉类类型中，只有牛肉的食用（相对危险度=1.006，95%可信区间=1.001-1.011，P=0.027）显示会影响弓形虫感染率。
