Antoniou M, Tzouvali H, Sifakis S, Galanakis E, Georgopoulou E, Tselentis Y
Laboratory of Clinical Bacteriology, Parasitology, Zoonoses and Geographical Medicine, Faculty of Medicine, University of Crete, Heraklion, Crete, 71003 Greece.
Parassitologia. 2007 Dec;49(4):231-3.
In Greece there are no official recommendations concerning the management of pregnant women for the prevention of congenital toxoplasmosis. A protocol for monitoring pregnant women was designed in order to differentiate between acute and latent toxoplasmosis and was tested successfully for 7 years. The maternofetal transmission rate in Crete was assessed and a map showing seroprevalence of pregnant women in all prefectures of Greece was prepared. The high seroprevalence of Toxoplasma gondii in Greece (up to 46% in some areas) may be explained by: (a) the presence of a great number of stray cats; (b) the Greek diet consisting of large amounts of raw, wild vegetables and salads that could easily be contaminated with oocysts; (c) the high consumption of meat, smoked pork and sausages, well-documented sources of T. gondii infection. T. gondii genotypes were characterized, directly from clinical samples, after PCR-RFLP on the SAG2 gene and sequence analysis at the restriction sites. They belonged to all 3 clonal lineages.
在希腊，没有关于管理孕妇以预防先天性弓形虫病的官方建议。设计了一项监测孕妇的方案，以区分急性和潜伏性弓形虫病，并成功测试了7年。评估了克里特岛的母婴传播率，并绘制了希腊所有行政区孕妇血清阳性率地图。希腊弓形虫的高血清阳性率（某些地区高达46%）可能由以下原因解释：（a）存在大量流浪猫；（b）希腊饮食包含大量可能容易被卵囊污染的生野生蔬菜和沙拉；（c）肉类、烟熏猪肉和香肠的高消费量，这些都是弓形虫感染的充分记录来源。通过对SAG2基因进行PCR-RFLP并在限制性位点进行序列分析，直接从临床样本中鉴定弓形虫基因型。它们属于所有3个克隆谱系。
